Exercise, Nutrition, and Health
Prof. Kuo received interdisciplinary Ph.D. degree in Exercise Physiology, Molecular Biology, and Biochemistry from University of Texas at Austin in 1997. He is appointed as Distinguished Professor in Institute of Sports Sciences at University of Taipei and serves as President of Taiwan Society for Sports Nutrition and Associate Editor for Journal of Traditional and Complementary Medicine. His research interest is how nutritional and phytomedicinal interventions influence exercise-induced muscle inflammation and cell senescence in human skeletal muscle of adults. Senescent cell accumulation implicates functional decay during aging in multicellular systems. Phagocytic macrophage is responsible for selective removal of senescent cells. His recent findings are : 1) Discovery of senescent cells (mostly CD34+/p16INK4a+ endothelial progenitor cells) in human skeletal muscle of young adults; 2) Transient elimination of the senescent cells in human skeletal muscle during resistance exercise; 3) Exercise-induced phagocytosis sustained by low protein availability; 4) Significant senescent cell (beta-galactosidase) elimination with endurance improvement in exercising skeletal muscle by a phagocytosis activator Rg1 (a steroidal compound from ginseng) supplemented before aerobic cycling. The modern society has increasingly demanding healthy and convenient lifestyle solutions. His research aims to provide options that meet this need of growing interest in nutritional and phytomedicinal products for recreational and lifestyle users.